Cenforce 50mg works by inhibiting the enzyme PDE5, which regulates blood flow in the penis. By blocking PDE5, the drug allows for increased blood flow to the penis during sexual stimulation, resulting in an erection. It helps relax the blood vessels in the penis, which improves blood flow and enhances erectile function. Cenforce 50mg should be taken orally with a glass of water. It is usually taken 30 minutes to an hour before sexual activity. The tablet can be taken with or without food, but taking it with a high-fat meal may delay the onset of its action.