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Kamagra 100mg works by inhibiting the action of the enzyme phosphodiesterase type 5 (PDE5) in the body. When sexually stimulated, the release of nitric oxide in the erectile tissue of the penis activates an enzyme called guanylate cyclase, which increases levels of cyclic guanosine monophosphate (cGMP). cGMP relaxes the smooth muscles in the blood vessels of the penis, allowing blood flow to the erectile tissue to increase and cause an erection. However, the PDE5 enzyme breaks down cGMP, leading to decreased blood flow and loss of erection. Sildenafil citrate in Kamagra 100 mg inhibits PDE5, allowing cGMP levels to remain high, thereby prolonging erection duration and firmness.